Process for preparation of chemically stable, dry-flow, low compact, dust free, soluble granules of phosphoroamidothioates

ABSTRACT

Dry flow, low compact, dust free, soluble granules of phosphoroamidothioates, preferably acephate, are produced by the process of 1) pre-mixing technical grade phosphoroamidothioate with specified adjuvants and other inert ingredients; 2) grinding to produce a ground product having a preferred particle size of 5 microns to 10 microns; 3) post-mixing; 4) granulating; 5) drying; 6) sizing to required length, preferably 1.5 to 3.0 mm; 7) and sieving to remove the fines to get the desired dust free soluble granule.

CROSS REFERENCE TO RELATED APPLICATION

This application claims the benefit, under 35 U.S.C. 119(e), of U.S.Provisional Application No. 60/340,272 filed Dec. 18, 2001, the contentsof which are incorporated herein by reference.

BACKGROUND OF THE INVENTION

1. Field of the Invention

The present invention relates to a process for preparing insecticidallyactive soluble granules of phosphoroamidothioate, referred to herein asacephate.

2. Background Information

In recent years, agricultural chemicals have been most preferablyformulated in the form of dusts, wettable powders, soluble powders,emulsifiable concentrates, soluble liquid/concentrates, granules, coatedgranules, water dispersible granules, suspension concentrates, andsolutions. Occasionally, when dusts are produced by absorbing or mixingactive ingredients with a finely divided inert carrier material, forexample China Clay or the like, drift problems occur. With wettablepowders and soluble powders the problems faced at the time of dilutionare not only drift, but the final disposal of containers, for dustparticles tend to stick to sides of the containers. The left overmaterials within the containers pose great problems to the environment,operators and users.

Although dusts are undesirable because of airborne contamination andhandling difficulties, liquid spray formulations have not provided anacceptable alternative, for they involve solvents and packagingexpenses, along with container disposal requirements that detract fromtheir commercial desirability.

Water dispersible granules produced by fluidized bed spray dryersovercome the problems associated with wettable powders and solublepowders, but have high processing costs and require high value capitalinvestment, as well as requiring highly skilled staff. These problemsimpose a significant barrier in widening the market acceptance of thesecompounds.

Certain phosphoroamidothioates and phosphoroamidodithioates,collectively referred to as Phosphoroamidothioates, are known to haveexcellent insecticidal activity against a variety of insects and in avariety of environments. Acephate, one of the important commercialinsecticides within this class of compounds, is a systemic and contactinsecticide of moderate persistence with residual activity lasting about10-15 days. It is effective against a wide range of aphids, leaf-miners,lepidopterous, larvae, sawflies and thrips and it is also anon-phytotoxic on many crop plants.

Phosphoroamidothioate containing pellets have been proposed in the past,but difficulties have been encountered in pelletizing acephatetechnical, the preferred insecticide within the class ofphosphoroamidothioates. Attempts to manufacture acephate technicalpellets from acephate technical powders have been proposed and have beenunsuccessful.

Considerable experimentation in the area of producing the preferredhigh-strength acephate granules has been conducted and confirms themanufacturing difficulties which earlier formulators have experienced.Furthermore, the pellets and methods proposed for making pelletssuggested in the prior art leave considerable room for improvement.Prior extrusion processes have proposed the addition of costlysurfactants, the combination of phosphoroamidothioate with a secondactive ingredient, or the creation of a mixture of the active ingredientwith a solvent in an amount of from 3-25% by weight before extrusion,but these processes have not solved the problems encountered.

The formulation of acephate presently in use is acephate 75% solublepowder having acephate active ingredient 75% (w/w), surfactant 1 to 2%(w/w), inert filler (precipitated silica) to make 100% (w/w). Acephate75% soluble powder poses the problems of dust, low pourability, hightransportation costs, high capital manufacturing investment, measurementdifficulties, difficulties in packing material disposal, handlingproblems, high risk of caking and others.

Because of the problems associated with producing granular forms ofphosphoroamidothioates, such as the preferred acephate, there is a needin the art for a process for preparing chemically stable, dry flow, lowcompact, dust free, insecticidally active soluble granules ofphosphoroamidothioate which are useful from a practical stand point, aswell as for a low cost, practical manufacturing technique which can bepracticed on a commercial scale without requiring expensive additives orsolvents.

SUMMARY OF THE INVENTION.

By the present invention the above-identified major limitations havebeen overcome. The method for producing dry flow, low-compact, dustfree, soluble phosphoroamidothioate granules, such as the preferredcompound acephate, is an improvement over prior manufacturing processes.Further, the dust free soluble granules produced by this invention,which has a concentration of the insecticidally active ingredient inthis formulation may vary from 40-98% of phosphoroamidothioate activeingredient, is more advantageous than prior granular products andexhibits certain very desirable characteristics as noted hereinafter.

Briefly, and in accordance with a preferred embodiment of the invention,dry flow, low compact, dust free, soluble granules of insecticiallyactive phosphoroamidothioate are prepared by forming a pre-mixcontaining the required quantity of phosphoroamidothioate, a dispersingagent, a wetting agent, a binding agent, an antifoaming agent, adisintegrating agent, a stabilizer and filler. The specified adjuvantshave a maximum of 1% water insoluble matter. This pre-mix is then groundto produce a ground product having preferred particle sizes between 5.0microns to 10.0 microns. The ground product is fed to a post-mixer toform a mixture. The mixture is then fed through a hopper into agranulator where granules are formed. The granules are then dried, andthe dried granules are sized and sieved to separate dry granules fromfines, producing dry flow, low compact, dust free, soluble granules ofphosphoro-amidothioate as noted above, the preferredphosphoroamidothioate is acephate. The fines may be recycled back to thepost mixer.

This invention produces essentially dry flow, low compact, dust freesoluble phosphoroamidothioate granules having a preferred granule sizeof 1.5 to 3.0 mm in length and 0.5 to 1.0 mm in diameter. These granulesof phosphoroamidothioates are characterized by aging stability for aminimum of two years.

BRIEF DESCRIPTION OF THE DRAWINGS

The features and advantages of the present invention will becomeapparent from the following detailed description of preferredembodiments thereof, taken in conjunction with the accompanyingdrawings, in which:

FIG. 1 is a flow chart of the preferred embodiment of the presentinvention.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

The process of the present invention is best described by referring tothe flow chart in FIG. 1. An essentially dry pre-mix comprising about95% to 99% of solids and 1% to 5% moisture and/or solvent is formed fromthe following ingredients: 40% to 98% of the insecticidally activecompound 2, 0.1% to 5.0% dispersing agent 4, 0.1% to 3.0% wetting agent6, 0.1% to 3.0% binding agent 8, 0.01% to 0.08% antifoaming agent 10,0.01% to 10.0% disintegrating agent 12, 0.01% to 1.0% stabilizer 14, andfillers 16 to make 100% (w/w). The insecticidally active compounds ofthe present invention have the following formula:

wherein R and R¹ individually are an alkyl, alkenyl or alkynyl groupcontaining upto 6 carbon atoms, R² is hydrogen, an alkyl groupcontaining 1 to 18 carbon atoms, a cycloalkyl group containing 3 to 8carbon atoms, an alkenyl group containins 2 to 18 carbon atoms or analkynyl group containing 3 to 18 carbon atoms, R³ is hydrogen or analkyl group containing 1 to 6 carbon atoms, and Y is oxygen or sulfur.All of the inert ingredients are preferably solids and in a powder form.In one preferred embodiment, the binding agent 8 is selected fromsucrose and starch derivatives or a blend thereof, the wetting agent 6is selected from calcium or sodium salt of alkyl aryl sulphonate, thedispersing agent 4 is selected from the derivative of sulfonated fattyalcohols, the disintegrating agent 12 is selected from swelling typeclays such as Bentonite and zeolite, the antifoaming agent 10 isselected from silicon oil derivatives, the stabiliser 14 is selectedfrom salts of higher fatty acids, and the filler 16 is selected fromprecipitated silica and kaoline and the like. Grinding 22 of the pre-mix20 is then conducted, preferably in a microniser, to obtain a groundproduct 24 having a preferred particle size of 5 microns to 10 microns.

The ground product 24 is subjected to post-mixing 26 to form a mixture28 which is then made into granules 36 by preferably charging 30, by wayof a rotary feeder, a feeding hopper which supplies the mixture to agranulator for granulation 34. The granulator that performs thegranulation 34 has a preferred inlet temperature between 30 to 35° C.and a preferred outlet temperature of between 40° C. to 45° C. Theresulting granules 36 are subjected to a drying 38 process, preferablyby passing the granules 36 through an air chamber, producing drygranules 40.

Sizing 42 the dry granules 40 is then accomplished to produce sizedgranules 44 of a desired length and diameter. Sizing the granules ispreferably conducted by passing the dry granules 40 through anoscillating cutter to obtain granules which are preferably between about1.5 mm and 3.0 mm in length and 0.5 mm to 1.0 mm in diameter. Aftersizing, the sized granules 44 are subjected to sieving 46 to separatefines 50 generated during the sizing process from desired dust freesoluble granules 51.

The fines 50 from the sieving 46 process may be collected and recycledat the charging 30 stage of the process to obtain a minimum yield of99.0% dry flowable, low compact, dust free, soluble granules 54 ofphosphoroamidothioates, preferably acephate.

The dust free soluble granules 54 were tested for required qualityspecifications and packed in desired packing. This technique gives 99%of conversion yield. The dust free soluble granules 54 enjoy all theformulation advantages described above, producing dust free solublegranules 54 which are beneficial from an economic aspect and a handlingaspect and which show a very good performance during use.

The following examples are presented to illustrate but not to restrictthe present invention. Parts and percentage are by weight unlessotherwise specified.

EXAMPLE 1

Acephate 97% Granules can be prepared as follows:

Composition

Ingredients Quantity (% w/w) Acephate Technical 98.5% purity 98.48Dispersing agent 0.50 Wetting agent 0.10 Binding agent 0.10 Antifoamingagent 0.03 Disintegrating agent 0.50 Stabilizer 0.05 Filler 0.24 Total100.00

EXAMPLE 1 PROCESS

The constituents of the above composition are mixed in a pre-mixer, thenground in a microniser to the required size of 5 micron to 10 micron.The ground product 24 is again mixed in a post-mixer to get a uniformhomogeneous mixture 28. This homogeneous mixture 28 is then fed througha rotary feeder into a low compaction granulator, while maintaining aninlet temperature of 32 to 35° C. and an outlet temperature of 40 to 45°C. The Acephate granules 36 formed in the granulator are further driedthrough an air chamber, sized to 1.5 mm to 3 mm length, and arecollected. The fines 50 generated during the process are recharged toget a conversion yield of 99 percent.

EXAMPLE 2

Acephate 98% granules can be prepared as follows:

Composition

Ingredient Quantity (% w/w) Acephate Technical 98.5% purity 99.50Dispersing agent 0.25 Wetting agent 0.03 Binding agent 0.05 Antifoamingagent 0.02 Disintegrating agent 0.05 Stabilizer 0.05 Filler 0.05 Total100.00

Acephate 98% granules with above composition can be prepared byfollowing the process described in EXAMPLE 1.

EXAMPLE 3

Acephate 97.5% granules can be prepared as follows:

Composition

Ingredient Quantity (% w/w) Acephate Technical 98.5% purity 98.99Dispersing agent 0.40 Wetting agent 0.10 Binding agent 0.10 Antifoamingagent 0.03 Disintegrating agent 0.20 Stabilizer 0.05 Filler 0.13 Total100.00

Acephate 97.5% granules with above composition can be prepared byfollowing the process described in EXAMPLE 1.

EXAMPLE 4

Acephate 90% Granules can be prepared as follows:

Composition

Ingredient Quantity (% w/w) Acephate Technical 98.5% purity 91.38Dispersing agent 00.75 Wetting agent 00.10 Binding agent 00.20Antifoaming agent 00.03 Disintegrating agent 01.00 Stabilizer 00.50Filler 06.04 Total 100.00

Acephate 90% granules with above composition can be prepared byfollowing the process described in EXAMPLE 1.

EXAMPLE 5

Acephate 85% granules can be prepared as follows:

Composition

Ingredient Quantity (% w/w) Acephate Technical 98.5% purity 86.30Dispersing agent 01.50 Wetting agent 00.50 Binding agent 01.00Antifoamer 00.05 Disintegrating agent 02.00 Stabilizer 00.60 Filler08.05 Total 100.00

Acephate 85% granules with above composition can be prepared byfollowing the process described in EXAMPLE 1.

EXAMPLE 6

Acephate 75% Granules can be prepared as follows:

Composition

Ingredient Quantity (% w/w) Acephate Technical 98.5% purity 76.15Dispersing agent 2.00 Wetting agent 1.50 Binding agent 1.50 Antifoamingagent 0.06 Disintegrating agent 5.00 Stabilizer 0.75 Filler 13.04 Total100.00

Acephate 75% Granules with above composition can be prepared byfollowing the process described in EXAMPLE 1.

EXAMPLE 7

Acephate 50% Granules can be prepared as follows:

Composition

Ingredients Quantity (% w/w) Acephate Technical 98.5% purity 50.77Dispersing agent 3.00 Wetting agent 2.00 Binding agent 3.00 Antifoamingagent 0.08 Disintegrating agent 10.00 Stabilizer 1.00 Filler 30.15 Total100.00

Acephate 50% Granules with above composition can be prepared byfollowing the process described in EXAMPLE 1.

EXAMPLE 8

Acephate 40% granules can be prepared as follows:

Composition

Ingredient Quantity (% w/w) Acephate Technical 98.5% purity 40.61Dispersing agent 4.50 Wetting agent 3.00 Binding agent 3.00 Antifoamingagent 0.08 Disintegrating agent 12.00 Stabilizer 1.50 Filler 35.31 Total100.00

Acephate 40% Granules of above composition can be prepared by followingthe process described in EXAMPLE 1.

Tests

The physical properties of Acephate granules were determined before andafter aging at 45° C. for 500 hrs and for flowability, wetting time,attrition test, disintegration rate, tap density, suspensibility,sedimentation and persistent foam. No noticeable difference in all theabove properties was observed. The dynamic wetting time and solubilitytest was measured as per MT-167 of CIPAC. The flowability was measuredas per MT-172 of CIPAC. The dry sieve analysis was measured as perMT-170 of CIPAC. The sedimentation was measured as per MT-15.1 of CIPAC.Dustiness of granules was measured as per MT-171 of CIPAC. The tapdensity was measured as per MT-58.4 and MT-33 of CIPAC. The Acephatetechnical was determined by the GLC method published in AOAC.

Although the present invention has been disclosed in terms of apreferred embodiment, it will be understood that numerous additionalmodifications and variations can be made without departing from thescope of the invention as defined by the following claims.

1. A process for preparing soluble granules comprising a) premixing 40to 98 wt. % an insecticidally active compound of the following formula:

wherein R and R¹ individually are an alkyl, alkenyl or alkynyl groupcontaining up to 6 carbon atoms, R² is hydrogen, an alkyl groupcontaining 1 to 18 carbon atoms, a cycloalkyl group containing 3 to 8carbon atoms, an alkenyl group containing 2 to 18 carbon atoms or analkynyl group containing 3 to 18 carbon atoms, R³ is hydrogen or analkyl group containing 1 to 6 carbon atoms, and Y is oxygen or sulfur;0.1-5.0 wt. % a dispersing agent; 0.1-3.0 wt. % a wetting agent; 0.1-3.0wt. % a binding agent; 0.01-0.08 wt. % an antifoaming agent; 0.01-10.0wt. % a disintegrating agent; 0.01-1.0 wt. % a stabilizer; and fillersto make 100 wt. %, to form a premix comprising essentially 95-99% solidsand 1-5% moisture and/or solids; b) grinding said premix to produce aground product having a predetermined particle size; c) post-mixing saidground product to produce a mixture; d) granulating said mixture toproduce granules; e) drying said granules to produce dry granules; f)sizing said dry granules to produce sized granules having apredetermined length and a predetermined diameter; and g) sieving saidsized granules to separate fines which are less than said predeterminedlength and said predetermined diameter.
 2. The process of claim 1,wherein said ground product has a predetermined particle size of 5-10microns.
 3. The process of claim 1, wherein said dry granules have apredetermined length of 1.5-3.0 mm.
 4. The process of claim 1, whereinsaid dry granules have a predetermined diameter of 0.5 to 1.0 mm.
 5. Theprocess claimed in claim 1, wherein said fillers are solids in powderform.
 6. The process of claim 1, wherein said binding agent is a blendof sucrose and starch derivatives.
 7. The process of claim 1, whereinsaid wetting agent is selected from the group comprising calcium salt ofalkyl aryl sulphonate and sodium salt of alkyl aryl sulphonate.
 8. Theprocess of claim 1, wherein said dispersing agent is a derivative ofsulfonated fatty alcohol.
 9. The process of claim 1, wherein saiddisintegrating agent is a swelling type clay selected from the groupcomprising bentonite and zeolite.
 10. The process of claim 1, whereinsaid antifoaming agent is silicon oil derivative.
 11. The process ofclaim 1, wherein said stabilizer is a salt of a higher fatty acid. 12.The process of claim 1, wherein said fillers are selected from the groupcomprising precipitated silica and kaoline.
 13. The process of claim 1,wherein said granulation is accomplished by passing said mixture throughan orifice having and inlet and an outlet.
 14. The process of claim 13,wherein said inlet has a temperature of 30-35° C.
 15. The process ofclaim 13, wherein said outlet has a temperature of 40-45° C.
 16. Theprocess of claim 1, wherein said drying is accomplished by passing saidgranules though an air chamber.
 17. The process of claim 1, wherein saidgrinding is accomplished by a microniser.
 18. The process of claim 1,wherein said sizing is accomplished by an oscillating cutter.
 19. Theprocess of claim 1, wherein said insecticidally active compound isacephate.
 20. The process of claim 1, further comprising; h) recyclingsaid fines into step d).
 21. The process of claim 20, wherein saidinsecticidally active compound is acephate.
 22. The process of claim 21,wherein said ground product has a predetermined particle size of 5-10microns.
 23. The process of claim 22, wherein said dry granules have apredetermined length of 1.5-3.0 mm and a predetermined diameter of 0.5to 1.0 mm.
 24. The process of claim 23, wherein said binding agent is ablend of sucrose and starch derivatives.
 25. The process of claim 24,wherein said wetting agent is selected from the group comprising calciumsalt of alkyl aryl sulphonate and sodium salt of alkyl aryl sulphonate.26. The process of claim 25, wherein said dispersing agent is aderivative of sulfonated fatty alcohol.
 27. The process of claim 26,wherein said disintegrating agent is a swelling type clay selected fromthe group comprising bentonite and zeolite.
 28. The process of claim 27,wherein said antifoaming agent is silicon oil derivative.
 29. Theprocess of claim 28, wherein said stabilizer is a salt of a higher fattyacid.
 30. The process of claim 29, wherein said fillers are selectedfrom the group comprising precipitated silica and kaoline.
 31. Theprocess of claim 20, wherein said granulation is accomplished by passingsaid mixture through an orifice having and inlet and an outlet.
 32. Theprocess of claim 31, wherein said inlet has a temperature of 30-35° C.and said outlet has a temperature of 40-45° C.
 33. The process of claim32, wherein said drying is accomplished by passing said granules thoughan air chamber.
 34. The process of claim 33, wherein said grinding isaccomplished by a microniser.
 35. The process of claim 34, wherein saidsizing is accomplished by an oscillating cutter.
 36. A process forpreparing soluble granules comprising a) preparing a dry premix bypremixing 40 to 98 wt. % an insecticidally active compound of thefollowing formula:

wherein R and R¹ individually are an alkyl, alkenyl or alkynyl groupcontaining up to 6 carbon atoms, R² is hydrogen, an alkyl groupcontaining 1 to 18 carbon atoms, a cycloalkyl group containing 3 to 8carbon atoms, an alkenyl group containing 2 to 18 carbon atoms or analkynyl group containing 3 to 18 carbon atoms, R³ is hydrogen or analkyl group containing 1 to 6 carbon atoms, and Y is oxygen or sulfur;0.1-3.0 wt. % a wetting agent and a filler to make 100 wt. %; b)grinding said dry premix to produce a ground product having apredetermined particle size; c) post-mixing said ground product toproduce a mixture; d) granulating said mixture to produce granules; e)drying said granules to produce dry granules; f) sizing said drygranules to produce granules having a predetermined length and apredetermined diameter; and g) sieving said sized granules to separatefines which are less than said predetermined length and saidpredetermined diameter.
 37. The process of claim 36, wherein saidwetting agent is selected from the group comprising calcium salt ofalkyl aryl sulphonate and sodium salt of alkyl aryl sulphonate.
 38. Theprocess of claim 36, wherein said filler is selected from the groupcomprising precipitated silica and kaoline.
 39. The process of claim 38,wherein said wetting agent is selected from the group comprising calciumsalt of alkyl aryl sulphonate and sodium salt of alkyl aryl sulphonate.40. The process of claim 36, wherein said step of preparing said drypremix further comprises premixing 0.1-5.0 wt. % a dispersing agent. 41.The process of claim 40, wherein said dispersing agent is a derivativeof sulfonated fatty alcohol.
 42. The process of claim 36, wherein saidstep of preparing said dry premix further comprises premixing 0.1-3.0wt. % a binding agent.
 43. The process of claim 42, wherein said bindingagent is a blend of sucrose and starch derivatives.
 44. The process ofclaim 36, wherein said step of preparing said dry premix furthercomprises premixing 0.01-0.08 wt. % an antifoaming agent.
 45. Theprocess of claim 44, wherein said antifoaming agent is a silicon oilderivative.
 46. The process of claim 36, wherein said step of preparingsaid dry premix further comprises premixing 0.01-10 wt. % adisintegrating agent.
 47. The process of claim 46, wherein saiddisintegrating agent is a swelling type clay selected from the groupcomprising bentonite and zeolite.
 48. The process of claim 36, whereinsaid step of preparing said dry premix further comprises premixing0.01-1.0 wt. % a stabilizer.
 49. The process of claim 48, wherein saidstabilizer is a salt of a higher fatty acid.
 50. The process of claim36, wherein said insecticidally active compound is acephate.
 51. Theprocess of claim 36, further comprising; h) recycling said fines intostep d).
 52. The process of claim 51, wherein said insecticidally activecompound is acephate.
 53. The process of claim 36, wherein said drypremix is substantially free from water or solvent.
 54. The process ofclaim 36, wherein said step of preparing said dry premix furthercomprises premixing 0.1-5.0 wt. % a dispersing agent, 0.1-3.0 wt. % abinding agent, 0.01-0.08 wt. % an antifoaming agent, 0.01-10 wt. % adisintegrating agent, 0.01-1.0 wt. % a stabilizer.
 55. The process ofclaim 54, wherein said insecticidally active compound is acephate. 56.The process of claim 55, wherein said dispersing agent is a derivativeof sulfonated fatty alcohol, said binding agent is a blend of socroseand starch derivatives, said antifoaming agent is a silicon oilderivative, said disintegrating agent is selected from the groupcomprising bentonite and zeolite, and said stabilizer is a salt of ahigher fatty acid.
 57. The process of claim 56, wherein said dry premixis substantially free of water or solvent.
 58. The process of claim 54,wherein said dry premix is substantially free of water or solvent.
 59. Aprocess for preparing soluble granules consisting essentially, a)preparing a dry premix by premixing 40 to 98 wt. % an insecticidallyactive compound of the following formula:

wherein R and R¹ individually are an alkyl, alkenyl or alkynyl groupcontaining up to 6 carbon atoms, R² is hydrogen, an alkyl groupcontaining 1 to 18 carbon atoms, a cycloalkyl group containing 3 to 8carbon atoms, an alkenyl group containing 2 to 18 carbon atoms or analkynyl group containing 3 to 18 carbon atoms, R³ is hydrogen or analkyl group containing 1 to 6 carbon atoms, and Y is oxygen or sulfur;0.1-5.0 wt. % a dispersing agent; 0.1-3.0 wt. % a wetting agent; 0.1-3.0wt. % a binding agent; 0.01-0.08 wt. % an antifoaming agent; 0.01-10.0wt. % a disintegrating agent; 0.01-1.0 wt. % a stabilizer; and a fillerto make 100 wt. %; b) grinding said dry premix to produce a groundproduct having a predetermined particle size; c) post-mixing said groundproduct to produce a mixture; d) granulating said mixture to producegranules; e) drying said granules to produce dry granules; f) sizingsaid dry granules to produce granules having a predetermined length anda predetermined diameter; and g) sieving said sized granules to separatefines which are less than said predetermined length and saidpredetermined diameter.
 60. The process of claim 59, wherein saidbinding agent is a blend of sucrose and starch derivatives.
 61. Theprocess of claim 59, wherein said wetting agent is selected from thegroup comprising calcium salt of alkyl aryl sulphonate and sodium saltof alkyl aryl sulphonate.
 62. The process of claim 59, wherein saiddispersing agent is a derivative of sulfonated fatty alcohol.
 63. Theprocess of claim 59, wherein said disintegrating agent is a swellingtype clay selected from the group comprising bentonite and zeolite. 64.The process of claim 59, wherein said antifoaming agent is silicon oilderivative.
 65. The process of claim 59, wherein said stabilizer is asalt of a higher fatty acid.
 66. The process of claim 59, wherein saidfiller is selected from the group comprising precipitated silica andkaoline.
 67. The process of claim 59, wherein said insecticidally activecompound is acephate.
 68. The process of claim 59, wherein said drypremix is substantially free of water or solvent.